Grimes had been listed as questionable and practiced on a limited basis. But the team elected to make him inactive Sunday morning.
Dominique Franks will start in Grimes’ place and Christopher Owens will be the third cornerback.
Starting linebacker Stephen Nicholas also will miss the game. That was expected because Nicholas was listed as doubtful with a toe injury and did not practice at all during the week. Spencer Adkins will start in his place.