Lawson did not practice this week after leaving last Sunday's win against Miami with a hamstring injury. Head coach Doug Marrone said Lawson suffered a setback in his recovery this week.
Meanwhile, the Bills listed running back Fred Jackson (knee) as probable for Sunday's game.
Full Bills injury report from Friday:
QB EJ Manuel (knee)
RB C.J. Spiller (ankle)
LB Manny Lawson (hamstring)
RB Fred Jackson (knee)
DT Kyle Williams (Achilles)