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Posted by ESPN.com's Paul Kuharsky
Indianapolis Colts (7-4) at Cleveland Browns (4-7), 1 p.m. ET
When Jaguars center Brad Meester returned from a biceps injury earlier this year, Cleveland nose tackle Shaun Rogers mauled him in Cleveland's upset win over Jacksonville.
This week, Rogers won't be facing crafty Indianapolis veteran center Jeff Saturday, who's out with a calf injury. It's rookie sub Jamey Richard instead. It rates as the key matchup of the day. Peyton Manning will be getting rid of the ball in a hurry, like he usually does, and the Colts will look to run to the edges with their stretch play. But Rogers can still disrupt things by collapsing the middle.
During a four-game winning streak, Manning has been precise, completing 65.4 percent of his passes for 1,069 yards with nine touchdowns, one interception, three sacks and a 100.9 passer rating.
The Browns have done a pretty good job protecting their quarterbacks, yielding only 12 sacks. Dwight Freeney and Robert Mathis may not get to Derek Anderson, but they can apply the kind of heat that forces him into making questionable throws. It looks like Bob Sanders (knee) will be missing from the secondary again.
Jacksonville Jaguars (4-7) at Houston Texans (4-7), 8:30 p.m. ET Monday
Who heads into the final four games of the season in last place of the AFC South?
It sure feels as if the Jaguars have more quit in them than the Texans do. And Houston probably has more to prove and more motivation in the franchise's first "Monday Night Football" game.
Back on Sept. 28, the Jags beat the Texans in Jacksonville, 30-27, in overtime. David Garrard threw for 236 yards and a touchdown and ran for 41 yards and another score. The Texans didn't sack him in that game, and more pressure will help their cause. Mario Williams has eight sacks this season but none in the last three games. Williams usually hops around and will get work against both of the Jaguars' tackles, Khalif Barnes and Tony Pashos.
The first quarter could tell the story for Jacksonville. According to ESPN Research, the Jaguars were 9-1 last season in games in which they held an opponent to no first-quarter points. This season, they are 3-5 when allowing at least seven points in the first quarter.