Pittsburgh Penguins (29-14-4) at New Jersey Devils (13-29-3), 7 p.m. ET
Season series: 2-0 Pittsburgh
Preview: The Penguins take the ice without both Sidney Crosby and Evgeni Malkin for the first time since Malkin came into the league, according to Elias Sports Bureau. Reports out of Pittsburgh indicate Malkin is day to day with a sore knee, while Crosby is still recovering from a concussion. Pens coach Dan Bylsma will put Dustin Jeffrey on the top line with Chris Kunitz and Pascal Dupuis. With a win tonight, Bylsma will tie Scotty Bowman for third place on the Penguins' all-time coaching wins list with 95.
Anaheim Ducks (26-19-4) at Toronto Maple Leafs (18-22-5), 7 p.m. ET
Preview: Jean-Sebastien Giguere will face his former team for the first time since being traded to Toronto. Giguere helped the Ducks to two Stanley Cup finals appearances, winning it all in 2007. Giguere is also the Ducks franchise leader among goalies for games played (447) and wins (206). The struggling Leafs are coming off a 7-0 loss to the Rangers on Wednesday night. Giguere said Wednesday morning that he would consider waiving his no-trade clause if the team asked.
New York Rangers (27-18-3) at Carolina Hurricanes (22-18-6), 7 p.m. ET
Season series: 1-1
Preview: The Rangers are coming off a 7-0 win on Wednesday night, but they are an impressive 10-2-0 this season when playing the second game of back-to-back games and haven't allowed more than three goals in the second games. The Hurricanes are sitting in ninth place in the East and trying to fight into the playoff picture, but have lost three of their past four.
Washington Capitals (25-14-8) at New York Islanders (14-23-7), 7 p.m. ET
Season series: 1-0 Washington
Preview: Looking the beat the Islanders for the ninth time in their past 10 meetings, the Capitals turn to Braden Holtby in net. Recalled from the Hershey Bears on Wednesday with both of Washington's two top goalies injured, Holtby will be making his fifth NHL start of the season. The Capitals have been held to three goals or fewer in 11 straight games and have one win in their past five games.
Ottawa Senators (17-23-7) at Philadelphia Flyers (30-11-5), 7 p.m. ET
Season series: 1-0 Philadelphia
Preview: Already leading the Eastern Conference, the Flyers now get to add top defenseman Chris Pronger back to the lineup. Pronger missed 13 games with a broken foot, but the Flyers went 9-4-0 in his absence and had the highest offensive production in the NHL at 3.46 goals per game. While Philadelphia is vying for the best record in the league, the Senators are tied with the Maple Leafs at the bottom of the Northeast due to a 1-6-3 stretch.
Tampa Bay Lightning (27-15-5) at Atlanta Thrashers (23-18-7), 7 p.m. ET
Season series: 4-0 Tampa Bay
Preview: With the Capitals struggling this season, the Southeast Division is wide open and the Lightning are taking advantage. Steven Stamkos has reclaimed the league goal-scoring lead with 35 goals after scoring in his past three games. Also, Stamkos has a point in seven of eight career games against the Thrashers with six goals and six assists.
Detroit Red Wings (28-12-6) at St. Louis Blues (22-17-6), 8 p.m. ET
Season series: 2-1 Detroit
Preview: The injury-riddled Red Wings will welcome back Jimmy Howard as they try to avoid a season-worst fourth consecutive road loss. Howard missed two games after bruising his right knee. And with Chris Osgood sidelined by a hernia, the Wings are in talks to sign goalie Evgeni Nabokov, a source confirmed to ESPN.com’s Pierre LeBrun on Thursday.
San Jose Sharks (23-19-5) at Vancouver Canucks (29-10-7), 10 p.m. ET
Season series: 2-0 Vancouver
Preview: After earning at least one point in a 17 straight games, the Canucks are just 1-2-1 in their past four games. The Canucks now return home from a five-game road trip with a three-point advantage for the Western Conference lead. Vancouver has outscored San Jose 10-4 in two meetings this season, but the Sharks come into the game on a two-game winning streak.