Wolff missed four games after injuring his right knee in Green Bay Nov. 10. He returned for last week's game against Chicago but left after playing one series. Veteran Patrick Chung will start at safety in place of the rookie.
Offensive lineman Matt Tobin is active for the second time this season. He takes Vandervelde's spot on the 46-man roster, but would not play center if anything happened to starter Jason Kelce. That role would likely fall to left guard Evan Mathis.
As expected, Cowboys quarterback Tony Romo and inside linebacker Sean Lee are inactive. So is former Eagle Ernie Sims, which leaves Dallas even thinner at linebacker.