Seth MacFarlane hosted the season opener of NBC's "Saturday Night Live" this week. The creator of "American Dad," "Family Guy" and the director of "Ted" appeared in several skits. He delivered a devastating send-up of Olympic swimming gold medalist Ryan Lochte trying to preview the upcoming TV season during "Weekend Update" with Seth Meyers.

Thanks to @sethmacfarlane for a great show.And for playing Ryan Lochte hulu.com/watch/401526#i…

— Seth Meyers (@sethmeyers21) September 16, 2012

"I was America in the Olympics" - Seth MacFarlane as Ryan Lochte #snl

— Kevin Daly (@kevinddaly) September 16, 2012

Today's picks coming, but first: How great was Seth MacFarlane last night on #SNL? The Ryan Lochte bit was off the charts.

— Mike Greenberg (@Espngreeny) September 16, 2012

MacFarlane, who was born in Connecticut and went to the Rhode Island School of Design, delivered the show's closing wearing a black and green Red Sox cap.

Lochte was not impressed. "Well I gotta admit that was a pretty harsh one, but it’s cool to have Seth parody me,” he told Celebuzz. “I think he pegged me wrong, but when I heard he did a skit I knew I was in for it.” Lochte appeared at the ALMA Awards show in Pasadena, Calif., Sunday night. Lochte, whose mother was Cuban, was honored with Latino Olympic medalists Danell Leyva, Brenda Villa, Jessica Steffens, Leo Manzano and Marlen Esparza, all of whom took the stage while wearing their medals. According to E! Online, co-host George Lopez also got some laughs at Lochte's expense. "Your mom is Cuban?" he asked the Olympian. "Now the swimming makes sense."

That show airs Friday on NBC.