Dunlap was replaced in the second half by D.J. Fluker, who moved from right tackle to left tackle. Jeromey Clary bumped out from right guard to right tackle and Chad Rinehart came in to play right guard.
San Diego Chargers coach Mike McCoy said doctors are still trying to determine if Dunlap suffered a concussion.
"We erred on the side of precaution there," McCoy said about Dunlap's injury. "He had some symptoms on the sideline -- obviously it was the first drive of the second half there -- that kind of just came on shortly before we were entering the field. So we erred on the side of precaution to take him out."
McCoy said he's not ruling a concussion out, and Dunlap has not been placed in the league's concussion program this week.
"We'll definitely look at what's the best interest of King Dunlap's future, and not just our football team, McCoy said.
McCoy did not provide an update on other injured players, saying they were still being evaluated and he would provide an update on Wednesday.
McCoy said the team had to make a tough decision in leaving outside linebacker Jarret Johnson (hamstring) off of the active roster for the Denver game.
"He was very close," McCoy said about Johnson. "And once again it's never fun sitting him down and saying, ‘Hey listen, we've got to look at the best interest of the team, No. 1. And for you, there's a lot of football left.'"
McCoy went on to say that the team wants to have Johnson available for the rest of the season.
With Johnson out, McCoy said rookie Tourek Williams played well, making a big play on a strip sack of Peyton Manning that led to a touchdown for the Chargers.
"He's one of the young guys on our team -- and there's a number of them -- that's getting an opportunity to play right now and throughout the whole season," McCoy said. "Because of the injuries and stuff, some guys have been forced into a role. And he did a great job of coming off the backside edge and staying alive. He had an opportunity to not only tackle him but strip it, and that's what he did. It was a huge point in the game, and it led to seven points for the offense. And we've got to do more of that as a defense. So I was very happy with the way he played.
"He's got a long ways to go. There were some mistakes he made, and sometimes he's out there and you're not sure what direction he's going. But that's in a young player, and he made the most of that opportunity."