This is a homecoming for Luck and a reunion for both men. Luck played for Harbaugh at nearby Stanford. They were the toast of college football, and Harbaugh played it into a job with the 49ers after the 2010 season. Luck stayed on The Farm another year and had a brilliant rookie season last year.
Indianapolis Colts at San Francisco 49ers
Sunday, 4:25 p.m. ET
However, there is much more than the Harbaugh-Luck angle in this game, as both 2012 playoff teams are coming off a loss in Week 2. Colts' reporter Mike Wells and I discuss the matchup in Double Coverage:
Wells: Quarterback Colin Kaepernick looked like he was more than a read-option quarterback when he threw for 412 yards in Week 1, but he was back to normal against Seattle, only throwing for 127 yards. Which game is the real Kaepernick -- the Week 1 performance or Week 2 at Seattle?
Williamson: I think he has shown the real Kaepernick is much closer to the one we saw against the Packers. The Seattle game was Kaepernick's worst in his 12 NFL starts. Kaepernick is still inexperienced and still growing. I think he will learn from the Seattle game. Plus, the Colts' defense is beatable in the air and on the ground. Kaepernick will likely bounce back. I expect to see Kaepernick have some success on the ground, similar to the success Oakland's Terrelle Pryor had against the Colts in Week 1.
Wells: Kaepernick will be a problem for the Colts. The only time the Colts had the answer for Pryor was when he decided to try to beat them with his arm instead of his feet. The Colts intercepted him twice, but I don't see them having that same kind of success against Kaepernick. He's a better runner and definitely a better passer than Pryor. You obviously cover Kaepernick on a daily basis, you know about Luck and you were in Seattle this week. Do you think the 49ers' quarterback deserves to be mentioned in the same breath as Luck, Russell Wilson and RG III?
Williamson: Oh, I'm a big Luck fan. As far as I'm concerned, the question should be whether the other young quarterbacks deserve to be mentioned in the same breath as Luck. Yes, he is a different quarterback than the other young stars. But this is what Luck has that will never go out of style -- he is a great pocket passer. He is a traditional star who would have been dominant in any era he played. I fancy myself as someone who stays grounded and doesn't speak bombastically about analysis. With that said, on the night Luck was drafted, I predicted his career will end with a ceremony in Canton, Ohio. I truly believe that and look forward to seeing him play in person for the first time Sunday.
Wells: Of course, this game became much more than Harbaugh and Luck when the Colts made the blockbuster deal for Richardson with Cleveland on Wednesday. Will the 49ers prepare as if they'll be facing Richardson on Sunday, or will they go in with the mindset that it'll be Ahmad Bradshaw and Donald Brown, since Richardson will only have two practices and a walk-through to learn Indianapolis' system?
Williamson: It definitely changed the 49ers' week. They are in a tough spot. They made their plan for the Colts and were actually executing it on the practice field for the first time when the trade went down. I don't think the 49ers totally changed their game plan because of the trade. But it altered it. Coaches suddenly had to watch film of Richardson and make adjustments. Because Richardson is a running back, I expect to see him a lot Sunday. He doesn't need a lot of time in the playbook. The Colts gave up a first-round pick for Richardson so they can win now. They will start using him when they can, and I'd think that will start Sunday. But the 49ers are good against the run. They were fourth in the NFL last season. They will attack this curveball with confidence.
Colts at 49ers: Stat of the Week
Something is going to give in the deep-passing game when the Colts have the ball. Andrew Luck's average pass attempt since the start of last season is an NFL-high 10.1 yards. Since the start of last season, opponents have attempted passes of 10 or more yards 164 times against the San Francisco defense. That is a league low.
Wells: Anything Richardson can give the Colts will be an upgrade over Brown, a former first-round pick who hasn't lived up to expectations. Bradshaw is still rounding into shape after not playing in the preseason, so having Richardson share some of the snaps with him will help the Colts' running game and hopefully open the passing game for Luck. The Colts are dealing with their fair share of injuries, losing starting tight end Dwayne Allen for the season. How big of a loss is nose tackle Ian Williams on defense for the 49ers?
Williamson: It hurts, but it's not devastating. Injuries happen to every team. Williams is a nice player and he was coming into his own. Free-agent pickup Glenn Dorsey was rotating with Williams. Now Dorsey is the starter. I think the 49ers will survive this injury as long as Dorsey stays healthy. There is not much depth behind him.
Wells: The Colts will test Dorsey, because Bradshaw and Richardson are both straight-ahead backs who run like they're angry at somebody. So much is being made about the Luck-Harbaugh reunion, but the real reunion is between brothers Vontae and Vernon Davis. Do you think Vernon will play with a purpose because his kid brother is on the field?
Williamson: It's really interesting, Mike. Vontae has been in the league since 2009, but this will be the brothers' first meeting. The Dolphins played the 49ers the year before they drafted Vontae, and they played the 49ers last season, shortly after dealing Vontae to the Colts. Vernon has been out of practice with a hamstring tweak. However, he has indicated he will play. I fully expect him out there. Vernon is a prime-time guy, and playing against his little brother will get his juices flowing. And of course, Harbaugh can tell Vernon all about the intensity of going against a sibling.
The final word on Sunday's matchup at Candlestick Park:
Mike Wells: The hype leading up to the game will be better than the game itself. The Colts are catching the 49ers at the wrong time. San Francisco is coming off a bad loss, and Indianapolis lost three starters in a week. 49ers 38, Colts 24
Bill Williamson: I think we will see the 49ers make amends with their home fans for the Seattle game. San Francisco will want to make a statement on offense that last week was simply a stumble. In the end, the 49ers and Harbaugh will have too much offense and too much defense for Luck in his homecoming. 49ers 34, Colts 20