GAINESVILLE, Fla. -- Florida struck quickly Saturday night. The first play from scrimmage, in fact.

But it was lights out for the Gators after that, as No. 3-ranked Alabama reeled off 35 unanswered points and romped past No. 12-ranked Florida 38-10 in the Swamp.

It was vintage Alabama, which made Florida one-dimensional on offense and then teed off on the Gators.

Florida quarterback John Brantley was injured just before halftime and didn't return. He was helped off the field, and the Gators' medical personnel were looking at his right lower leg. True freshman Jeff Driskel replaced Brantley and was under constant duress in the second half.

Junior running back Trent Richardson led the Crimson Tide (5-0, 2-0) with a season-high 181 rushing yards on 29 carries. He scored a pair of touchdowns, including a 36-yard sprint.

The Gators (4-1, 2-1) scored on a 65-yard touchdown pass from Brantley to Andre Debose on the first play from scrimmage. But from there, the Alabama defense locked down, and Florida managed just 157 total yards the rest of the way.

Alabama held Florida to 15 rushing yards on 29 attempts.

The Gators have now lost four out of their past five SEC games at home dating back to last season. It was also their worst home loss since bowing 36-7 to LSU in 2002.