Here is what we're looking at so far for Week 3:
John Skelton, Arizona Cardinals (ankle): Skelton missed Week 2 because of his ankle sprain, and Kevin Kolb started in his place. Will Kolb start again in Week 3? Early signs point to that being the case. While Skelton was "walking around," according to the Cardinals' official website, he did not practice Wednesday. Skelton did manage a limited practice Thursday, but it seems hardly enough to suggest he'll take over the reins again this weekend.
Ryan Mathews, San Diego Chargers (shoulder): Well, well, well. It looks like we are about to see the highly anticipated season debut of a certain Chargers running back. The timing does not come as a complete surprise, as it's consistent with the typical healing timeframe for this type of injury (fractured clavicle).
This is from my entry on Mathews in the 2012 Fantasy Football Draft Kit: "... Before a player is cleared to resume contact, there must be sufficient evidence of bony repair to alleviate concerns of reinjury. Every fall onto the shoulder, direct hit to the shoulder (especially if the player is hit from both sides simultaneously), even a stiff-arm move, will translate force through the collarbone area. For an athlete such as Mathews, who will incur contact through his clavicle (directly or indirectly) on virtually every play in which he carries the ball, the confidence that the bone will remain intact must be high before allowing him to compete. Normal bone healing takes approximately six weeks, which, given Mathews' injury date, would suggest he could be ready by Week 3."
Mathews was cleared for contact late last week but had very limited practice reps and was held out of competition for another week. That was smart. Now Mathews has had a chance to turn it up a notch in practice, and his collarbone has had another week of bone remodeling. According to the San Diego Union-Tribune, Mathews said, "I feel great; I feel healthy and strong." That's what fantasy owners like to hear.
Steven Jackson, St. Louis Rams, (groin): On Tuesday, we noted that Jackson missed time in Sunday's game because of a groin injury and nothing else. While coach Jeff Fisher and Jackson made it seem as though the injury was not serious -- and an MRI seemed to confirm as much -- it remains to be seen whether Jackson will be ready to go this weekend. He did not practice Wednesday or Thursday, but according to the Rams' official website, he "remains hopeful" he'll be ready by Sunday. This may well come down to a game-time decision.
Matt Forte, Chicago Bears (ankle): As we noted Tuesday, we said it would be a surprise to see Forte this week, and his non-participation in practice Wednesday or Thursday supports that idea. While it does seem that the injury was not as serious as initially expected, it's still looking like, barring a Friday surprise, Michael Bush will start for the Bears in Week 3.
Marshawn Lynch, Seattle Seahawks (back): Lynch has been on the injury report since prior to Week 1 because of his back. So far he has managed to play in the first two games of the season. Since the Seahawks play Monday night, there is only one day of practice (Thursday) to report so far, and Lynch again appeared as a limited participant. No reason for major concern as of now.
Jamaal Charles, Kansas City Chiefs (knee): Charles fell on his surgically reconstructed knee in Week 2 and sustained a knee bruise, according to the Kansas City Star. He was able to return to full practice Wednesday and followed it up again Thursday, boding well for him playing Sunday.
Rashard Mendenhall (knee) and Jonathan Dwyer (toe), Pittsburgh Steelers: Mendenhall has again been listed as a full participant in practice both Wednesday and Thursday this week. Here's what I said last week after he practiced both days: "Pittsburgh does have an early bye week (Week 4), and it's possible we do not see Mendenhall before then." I still feel the same way. Each week, Mendenhall has been exposed to increasingly more work and increasingly more contact. Like others coming off ACL surgery, there is a process for evaluating how the player -- and his knee -- responds to each upgrade in activity. There is nothing official from the team to indicate he will wait another week, so it remains possible that he could be activated. If that does happen, he would not likely get a heavy workload in his first outing.
Meanwhile, Dwyer is dealing with a case of turf toe, which may have hindered his productivity somewhat in Week 2. He rested Wednesday but was back in full practice Thursday, hinting at him being active for Week 3.
Rashad Jennings, Jaguars, (knee): Again this week, Jennings has not practiced due to a knee injury. It will be the Maurice Jones-Drew show on the ground in Indianapolis when the Jaguars visit the Colts regardless.
Daniel Thomas, Miami Dolphins (concussion): Thomas missed last week's game due to a concussion but returned to full practice Wednesday. Barring a setback, he should be available this weekend, although he will serve as a backup to Reggie Bush.
Calvin Johnson, Detroit Lions (ankle): Last week it was his foot, this week it's his ankle. Johnson will probably appear on the injury report fairly regularly; hopefully, he will continue the pattern of resting early in the week and playing later. He did not practice Wednesday but was back in limited practice Thursday. If he continues the trend, expect him to play Sunday.
Greg Jennings, Green Bay Packers (groin): Jennings sat out last week's game because of a groin injury. It wasn't much of a surprise considering he had suffered the injury just four days prior, The expectation was that the extra time off would have him in good shape for Week 3. In fact, coach Mike McCarthy told the Milwaukee Journal-Sentinel late last week he would be surprised if Jennings did not play in Monday night's contest.
Then came Tuesday's practice. Jennings was on the field in full pads, and all seemed to be progressing well. It turns out Jennings didn't do much Tuesday other than run, and on Thursday he was unable to practice at all. According to the Milwaukee Journal-Sentinel, McCarthy said Jennings was limited to rehab Thursday and was not progressing "as well as hoped." While there are still a few more days before game time, if Jennings is still this limited 11 days post-injury, how much improvement can realistically be expected by Monday? His status could come down to a game-time decision, but if he isn't able to practice at all Friday, fantasy owners should be concerned.
Jeremy Maclin (hip) and DeSean Jackson (hamstring), Philadelphia Eagles: These two were both on the Thursday injury report last week, and both ended up playing Sunday. The difference is that this week Maclin was forced out of the game because of his hip. Jackson finished the game -- and played well -- despite a hamstring strain late in the week. While Maclin was unable to practice Wednesday, he did return on a limited basis Thursday. Jackson practiced on a limited basis Wednesday and returned to full practice Thursday.
At this point, Jackson appears to be in better shape heading toward Sunday, presuming there are no setbacks beforehand. As far as Maclin's status is concerned, he does appear to be making progress and as long as he shows he can perform sufficiently before kickoff, there is still a reasonable chance he plays. Friday's practice should yield better clues for both receivers.
Pierre Garcon, Washington Redskins (foot): Even though he did not play Sunday, the rest might not have been enough for Garcon's foot. He participated in limited practice Wednesday and Thursday, but according to the Fredericksburg Free Lance-Star, coach Mike Shanahan says Garcon's injury is "nagging him a little bit more than I was hoping it would." That's certainly not the most optimistic sounding assessment. If Garcon continues to experience this level of discomfort, it's hard to imagine him suiting up in Week 3.
Marques Colston, New Orleans Saints (foot): Colston was listed on the injury report last week because of his foot, but still managed to play Sunday. According to the New Orleans Times-Picayune, Saints interim coach Aaron Kromer says the foot injury is affecting Colston's speed. Perhaps the limited reps in practice this week will help him get back up to speed. He is expected to play Sunday.
Julio Jones (thigh) and Roddy White (knee), Atlanta Falcons: Jones and White both on the injury report? Not to worry. The Atlanta Journal-Constitution reports that coach Mike Smith offered this explanation: "The reason a lot of those guys are limited in their participation is [because] we are on a short week." They did play Monday night, and it was, after all, a very long game. Both were restricted to limited work in practice Wednesday and Thursday, but from the sounds of things, both are expected to play Sunday.
Brandon Lloyd, New England Patriots (thigh): Lloyd was limited both Wednesday and Thursday with what is being listed as a thigh injury. There has been nothing to suggest the injury is serious, though, including the fact that Lloyd did not completely miss a practice. The Patriots do not play until Sunday night, so hopefully there will be a better indication after Friday's session.
Antonio Gates, Chargers (ribs): Despite missing Sunday's game due to sore ribs, Gates did get right into practice this week, an encouraging sign for this week's status. Although he was limited Wednesday, his response to practice was positive enough to bump him up to a full workload Thursday. Thankfully, it does not appear he will be a game-time decision this week.
Heath Miller, Pittsburgh Steelers (abdomen): Miller has not practiced yet this week because of a rib cartilage injury. Any injury in the rib area can be exceptionally painful; Antonio Gates missed last week's game with a similar ailment. This could come down to a game-time decision.
Dustin Keller, New York Jets (hamstring): Keller missed last week's game because of his hamstring injury but appears to be making progress. He wasn't in practice Wednesday but did return to limited work Thursday. Now the test will be to see how the leg responds and whether he can repeat the effort Friday.