Welker is now subject to the NFL's concussion protocol, which will include baseline testing Monday. However, even if Welker were to be cleared for activity this week with that exam, the protocol would preclude him from playing in Thursday night's game against the San Diego Chargers.
Following Sunday's game, Broncos coach John Fox called Welker's concussion "our only significant injury."
The concussion protocol states that a player who is cleared for activity the day after suffering the concussion can only take part in the non-contact portions of practice on Thursday and the first day of full participation in practice can be Friday following the injury.
It is the second concussion Welker has suffered in the last four games. Welker left the Nov. 17 win over the Kansas City Chiefs, but played the following week in New England.
He suffered Sunday's as he tried to go low to get a pass just before halftime. With 35 seconds remaining in the first half, Peyton Manning tried to hit Welker over the middle. Welker went low for the ball and Titans safety Bernard Pollard crashed into Welker's head and neck.
Welker had five catches for 61 yards and a touchdown when he left the game.
For the season Welker is second on the team in catches (73) and tied for second in touchdowns with 10. Tight end Jacob Tamme lined up in Welker's spot, in the slot, for the remainder of the game.