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Konerko had to have the fragment dislodged last season and missed two games because of the procedure. He is expected to return to the lineup on Wednesday.
"He had a wrist procedure," Ventura said after Tuesday's 9-5 loss. "It's happened before. They took care of it today. It's like the little chip that floats around in his wrist. They flushed it around. He was out today. He should be OK tomorrow."
Konerko leads the American League with a .366 average. He also has 11 home runs, 33 RBIs, a .445 on-base percentage and a .617 slugging percentage.
Konerko was scratched from the lineup about an hour prior to Tuesday's game. He was replaced by Brent Lillibridge at first base.