"He went back to Chicago for a family matter," Blackhawks coach Joel Quenneville said after the club's morning skate at Rogers Arena.
Quenneville, whose Blackhawks won 2-1 Saturday night in their third stop on a seven-game road trip, said he does not know when Hossa will rejoin the club.
Hossa, who has 10 goals and seven assists in 20 games this season, had just returned to the lineup Thursday in Winnipeg after missing three games with a lower-body injury, and tallied a goal and an assist in a 6-3 win over the Jets while logging just under 18 minutes of ice time.
Meanwhile, forward Michal Handzus, out since late October with a lower-body injury, took part in the morning skate and could return to the lineup Monday at Calgary.
"We expect him to be joining us real soon," Quenneville said.
Handzus, who has three points in nine games this season, was activated from injured reserve Saturday evening.