Frolik has missed two games due to an upper-body injury believed to be his shoulder while Seabrook has missed the past three with a left leg ailment.
"We'll know more after the morning skate [Wednesday]," coach Joel Quenneville said after practice on Tuesday. "Maybe we'll have a better indication."
Seabrook lost an edge, slamming into the end boards, in a game against the Edmonton Oilers on Nov. 13.
"It was all me. The boards came up quick," Seabrook said of falling. "[It's] feeling good. It's progressed every day. We'll see."
Though he hit the boards hard Seabrook said he didn't think it was a serious injury.
"You never fear the worst on things like that unless your arm is sticking out of your skin or something like that," Seabrook said. "I thought it was just a stinger or charley horse type thing."
Seabrook practiced with his regular defensive partner, Duncan Keith, but sat out a portion of one drill on Tuesday.
Frolik missed back-to-back games Friday and Saturday after sliding hard into the end boards in Vancouver last Wednesday. He was the "extra" forward during line rushes during practice.
Seabrook is anxious to play after sitting out the first three games on the Hawks' annual circus road trip.
"I hate it. I'm probably worse than anyone," he joked of having to watch. "The trainers all want to kill me. They're working hard to get me back on the ice so they can stop dealing with me."
The Hawks are 1-2 in the first half of a six-game road trip.
Jesse Rogers covers the Blackhawks for ESPN 1000 and ESPNChicago.com.