"Accuracy and adherence to Conference policies and officiating mechanics are vital to the proper administration of the rules in all games," said Walt Anderson, Big 12 supervisor of officials, in a statement. "Disciplinary actions will be addressed with both the field officials and chain crew."
In the final three minutes before halftime, Oklahoma State had a first-and-10 at the Kansas State 45-yard line. After a holding call, a sack and a 4-yard reception, the Cowboys faced third-and-23. Quarterback Mason Rudolph then completed a pass to Marcell Ateman for 19 yards.
The first-down marker, however, was mistakenly placed at the K-State 40, instead of the 35. Officials didn't catch the error, awarding the Cowboys a first down instead of a fourth-and-4.
Four plays later, Oklahoma State scored a touchdown to cut Kansas State's lead to 28-20 less than a minute before halftime. The Cowboys won the game on a 37-yard field goal in the final seconds.
Afterward, Kansas State coach Bill Snyder told the Kansas City Star that he had noticed the error but didn't elaborate.
"I am trying to think what the official told me about it," Snyder said. "I can't remember right now."
Big 12 officiating came under fire last week after Texas was flagged 16 times for 128 yards in a last-second loss to Oklahoma State. The most controversial sequence occurred when Texas defensive tackle Poona Ford was flagged for defensive holding on a running play late in the fourth quarter.
While arguing the holding call, Longhorns coach Charlie Strong was penalized for unsportsmanlike conduct by the line judge, who appeared to bump into Strong on the sideline immediately before throwing the flag.
Propelled by the two penalties, the Cowboys kicked a field goal to tie the game, then won it on the ensuing drive with another field goal after Texas botched a punt attempt.
Anderson defended the calls after reviewing the game, telling ESPN.com he was "generally pleased" with the officiating.
"You would have to call whoever the gentleman is who takes care of officiating," said OU defensive coordinator Mike Stoops when asked about the high number of penalties. "He said they were all good calls a week ago. It is what it is."