Lamb, a redshirt sophomore, injured his knee late in Sunday's 49-7 victory against Ohio. He had 13 yards on four carries and returned a fourth-quarter kickoff for 20 yards.
Strong said the injury was "tough" for a player who had worked to become part of Louisville's five-man backfield rotation.
The coach also said that redshirt freshman tight end Hunter Bowles will have neck surgery Thursday but wasn't specific about his status.
Copyright 2013 by The Associated Press
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