| Passing Leaders | |||||||||
| RK | NAME | TEAM | RESULT | COMP | ATT | YDS | TD | INT | RAT |
| 1 | Case Keenum, QB | HOU | W 30-14 at PSU | 45 | 69 | 532 | 3 | 0 | 144.3 |
| 2 | Blaine Gautier, QB | ULL | W 32-30 vs. SDSU | 24 | 40 | 470 | 3 | 1 | 178.5 |
| 3 | Alex Carder, QB | WMU | L 32-37 at PUR | 31 | 57 | 439 | 3 | 4 | 122.4 |
| 4 | Keith Price, QB | WASH | L 56-67 at BAY | 23 | 37 | 438 | 4 | 0 | 197.3 |
| 5 | Ryan Lindley, QB | SDSU | L 30-32 at ULL | 28 | 49 | 413 | 3 | 0 | 148.2 |
| 6 | Geno Smith, QB | WVU | W 70-33 at CLEM | 32 | 43 | 407 | 6 | 0 | 200.0 |
| 7 | Brandon Weeden, QB | OKST | W 41-38 vs. STAN | 29 | 42 | 399 | 3 | 1 | 167.7 |
| 8 | Brock Osweiler, QB | ASU | L 24-56 at BSU | 30 | 47 | 395 | 2 | 1 | 144.2 |
| 9 | Ryan Aplin, QB | ARST | L 20-38 at NIU | 30 | 58 | 353 | 1 | 3 | 98.2 |
| 10 | Andrew Luck, QB | STAN | L 38-41 at OKST | 27 | 31 | 347 | 2 | 1 | 196.0 |
| Rushing Leaders | |||||||||
| RK | NAME | TEAM | RESULT | CAR | YDS | YPC | TD | ||
| 1 | Terrance Ganaway, RB | BAY | W 67-56 vs. WASH | 21 | 200 | 9.5 | 5 | ||
| 2 | Lampford Mark, RB | NEV | L 17-24 at USM | 29 | 183 | 6.3 | 2 | ||
| 3 | Vick Ballard, RB | MSST | W 23-17 at WAKE | 14 | 180 | 12.9 | 2 | ||
| 4 | Stepfan Taylor, RB | STAN | L 38-41 at OKST | 35 | 177 | 5.1 | 2 | ||
| 5 | Montee Ball, RB | WIS | L 38-45 at ORE | 32 | 164 | 5.1 | 1 | ||
| 6 | LaMichael James, RB | ORE | W 45-38 vs. WIS | 25 | 159 | 6.4 | 1 | ||
| 7 | Michael Smith, RB | USU | L 23-24 vs. OHIO | 12 | 157 | 13.1 | 2 | ||
| 8 | De'Anthony Thomas, RB | ORE | W 45-38 vs. WIS | 2 | 155 | 77.5 | 2 | ||
| 9 | Doug Martin, RB | BSU | W 56-24 vs. ASU | 31 | 151 | 4.9 | 1 | ||
| 10 | Akeem Shavers, RB | PUR | W 37-32 vs. WMU | 22 | 149 | 6.8 | 0 | ||
| Receiving Leaders | |||||||||
| RK | NAME | TEAM | RESULT | REC | YDS | YPR | TD | ||
| 1 | Jordan White, WR | WMU | L 32-37 at PUR | 13 | 265 | 20.4 | 1 | ||
| 2 | Gerell Robinson, WR | ASU | L 24-56 at BSU | 13 | 241 | 18.5 | 1 | ||
| 3 | Patrick Edwards, WR | HOU | W 30-14 at PSU | 10 | 228 | 22.8 | 2 | ||
| 4 | Martel Moore, WR | NIU | W 38-20 vs. ARST | 8 | 224 | 28.0 | 1 | ||
| 5 | Tavarres King, WR | UGA | L 30-33 vs. MSU | 6 | 205 | 34.2 | 1 | ||
| 6 | Jermaine Kearse, WR | WASH | L 56-67 at BAY | 5 | 198 | 39.6 | 1 | ||
| 7 | Javone Lawson, WR | ULL | W 32-30 vs. SDSU | 9 | 193 | 21.4 | 2 | ||
| 8 | Justin Blackmon, WR | OKST | W 41-38 vs. STAN | 8 | 186 | 23.3 | 3 | ||
| 9 | Taylor Stockemer, WR | ARST | L 20-38 at NIU | 11 | 185 | 16.8 | 1 | ||
| 10 | Lavasier Tuinei, WR | ORE | W 45-38 vs. WIS | 8 | 158 | 19.8 | 2 | ||
