Hamilton, who did not play in Monday's game with upper respiratory issues and said he feels about the same as he did on Monday, hit his majors-best 21st homer and drove in all three runs for the Rangers.
"It's not going to get any worse," Hamilton said before the game. "I'll go out and play and see what happens. It will be fine."
Manager Ron Washington said Hamilton was at the ballpark early on Tuesday and said he wanted to play. Washington said he would watch Hamilton in batting practice and would see how he's feeling as the game is going.
"If I have to pull him off, I will and give him another day," Washington said.
Hamilton said he first began to feel the effects in Houston a week and a half ago. He played through it and after hitting a walk-off home run in the 13th inning against Toronto on Saturday, Hamilton needed intravenous fluids and some oxygen after the game.
Hamilton entered Tuesday 3 for 12 on the homestand with two homers and four RBIs.