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Hamilton County Sheriff Doug Carter said Daniell Harper, 31, was being held without bond on charges of battery with a deadly weapon and criminal recklessness.
Nick Harper was treated for a knee injury at St. Vincent Hospital in Indianapolis. His injuries were not life-threatening, Carter said.
Harper, a starter, is listed as active for Sunday's AFC divisional playoff game against Pittsburgh.
Earlier Saturday, Colts spokesman Craig Kelley said Harper had required stitches in his knee following an "accident." He said he had no other details.
Kelley told The Associated Press later that he had gotten his information from Colts officials.
"There was not an accident," Carter said. He said Harper and his wife had been involved in a fight.
Harper, 31, was arrested in June on a domestic battery charge after police said he hit his wife.Information from The Associated Press was used in this report.