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Starting center Eric Heitmann suffered a broken right tibia on a Frank Gore running play. Seahawks defensive end Darryl Tapp hit into the side of Heitmann's lower leg in the pileout after Gore made a 3-yard run to the Seahawks 7.
Heitmann had to be taken off the field in a cart. X-rays revealed the break that will end his season. Tony Wragge took his spot at center.
John Clayton is a senior writer for ESPN.com.