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|In December 2007 in Giants Stadium, Matt Cassell (left) and Bill Belichick celebrated the completion of a 16-0 Patriots' regular season under starting QB Tom Brady. Sunday, the duo will try to extend the Patriots' winning ways without Brady.|
Tom Brady's injury had a profound effect on Week 1 of the fantasy football season. Fans who started Brady lost 72 percent of Week 1 matchups. Meanwhile, Brady owners were scrambling for help on Monday. Of all trades completed on ESPN.com, 23 percent involved teams who owned Brady. More Fantasy Football
With Tom Brady's knee injury, the Patriots plummeted from an exclamation point of an unbeaten 2007 regular season to a huge question mark in 2008.
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