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Ole Miss senior defensive end Kentrell Lockett will miss Saturday's opener against Jacksonville State because of a heart-related ailment, and his status for the rest of the season is unknown at this point.
Head trainer Tim Mullins said Lockett has a "rhythm problem" with his heart. He began experiencing it during Saturday's scrimmage and was immediately cared for by local doctors. He has since seen specialists in Memphis and is now at a clinic in Cleveland, where further tests will be conducted throughout the week.
There is no timetable for Lockett's return before receiving results of the tests, but he's in stable condition, Ole Miss officials reported.
Lockett was taken off the field last Saturday after telling trainers that his heart was racing. He had a similar situation two years ago, according to Ole Miss coach Houston Nutt.
"We had a pretty big blow today with Kentrell Lockett," Nutt said. "He's in Ohio right now running some tests. It was a hard Tuesday because you've got so many things thrown at you in one day, but I like the way Gerald Rivers and Jason Jones stepped up. It's all hands on deck. You've got to work by committee now."
Ole Miss also learned on Tuesday that the NCAA had denied quarterback Jeremiah Masoli's request to be eligible this season.
Lockett, recently voted as one of the team captains, had started the last two seasons at defensive end. He led the Rebels last season with 13 quarterback pressures and was second on the team with 10 tackles for loss and five sacks.
Rivers will start in place of Lockett. The 6-foot-5, 245-pound sophomore played in five games last season.
Chris Low is a college football writer for ESPN.com.