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Quarterback, Baltimore RavensSo much for Flacco not being able to beat the Steelers. Flacco's first pass of the game was a 27-yard touchdown strike to Anquan Boldin. The fourth-year QB followed with two more TD passes, leading Baltimore to a 35-7 victory. It was Flacco's first head-to-head victory over Steelers QB Ben Roethlisberger (see below).
Running back, Baltimore RavensRice also had a big hand in the Ravens' victory. Rice, who exploded for a 36-yard run on the first play from scrimmage, scored a pair of TDs (one rushing, one receiving). He rushed for 107 yards on 19 carries and caught four passes for 42 yards.
Linebacker, Chicago BearsJay Cutler had a big game for the Bears (312 passing yards, 2 TDs), but he got plenty of help from Chicago's defense, specifically Urlacher. The veteran linebacker intercepted a Matt Ryan pass in the first quarter and returned a fumble 12 yards for a TD in the third as Chicago routed the Falcons 30-12. Urlacher also led Chicago with 10 tackles.
Quarterback, Buffalo BillsFitzpatrick's crisp passing allowed Buffalo to pull off an impressive upset at Arrowhead Stadium. Fitzpatrick threw four TD passes for the third time in his career, leading Buffalo to a 41-7 victory over the Chiefs. Fitzpatrick completed 17 of 25 passes for 208 yards.
Quarterback, Detroit LionsStafford shook off an early pick-six and guided the Lions to a 27-20 victory at Tampa Bay. Stafford completed 24 of 33 passes, including TD throws of 36 yards and 1 yard to Calvin Johnson and 11 yards to Tony Scheffler. The only interception he threw glanced off the hands of intended receiver Will Heller and was returned 28 yards by Aqib Talib for a score. Stafford became the first Lions quarterback since Bobby Layne in 1953 to have a 300-yard game in a season opener.
Quarterback, Carolina PanthersHis comeback bid fell short, but the rookie deserves a nod regardless. Newton passed for a whopping 422 yards, becoming the first rookie to throw for more than 400 yards in his regular-season debut, and two TDs in Carolina's 28-21 loss to the Cardinals. He completed 24 of 37 passes and also ran for 18 yards and a score.
Running back, Cincinnati BengalsThe Bengals have some instability at QB. Good thing for them they have a workhorse back. Benson rushed for 128 yards on 25 carries in Cincinnati's 27-17 victory over the Browns. His 39-yard TD run with 1:49 left put the game out of reach.
Kick returner, San Francisco 49ersGinn broke open a close game with two spectacular kick returns for TDs in the fourth quarter. Ginn returned a kickoff 102 yards for a score, then returned a punt 55 yards to pay dirt, sealing the 49ers' 33-17 victory over Seattle. The performance marked a phenomenal turnabout for Ginn, who left the 2010 opener with an injury that sidelined him for weeks.
Quarterback, Pittsburgh SteelersRoethlisberger suffered through what was probably his worst career outing against the Ravens' D. Roethlisberger threw three INTs and lost a pair of fumbles in the Steelers' loss. A good chunk of his 280 passing yards came after Baltimore built a commanding lead.
Running back, Tennessee TitansRecently rewarded with a new contract, Johnson failed to pay dividends in Week 1. Johnson was held to 24 yards on nine carries (2.7 yard average) in the Titans' 16-14 loss to the Jaguars.
Quarterback, Minnesota VikingsMcNabb's Vikings debut wasn't pretty. The veteran QB passed for only 39 yards (7-for-15) with one TD and one pick. His longest completion was 12 yards.