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Sources have confirmed to ESPN.com both fighters have agreed to the bout. The TUF 16 Finale is scheduled to take place at The Hard Rock Hotel and Casino.
Barry (7-5) hasn't fought since suffering a first-round TKO loss to Lavar Johnson at a UFC on Fox event in May. The 33-year-old heavyweight holds a 4-5 record in the UFC, with all five losses coming by way of knockout or submission.
Del Rosario (11-1) fell short in his UFC debut in May, taking a second-round TKO loss to Stipe Miocic at UFC 146. The California native entered the UFC after a strong run in Strikeforce, where he was 3-0, including a submission win over Johnson.
The 29-year-old prospect missed out on most of 2011 with injuries he suffered in a car accident.
Another heavyweight showdown between Roy Nelson and Shane Carwin is scheduled to headline the TUF 16 Finale.