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Indianapolis 25, Jacksonville 20
AFC South rivals clash over division lead
With the AFC South division lead hanging in the balance, Peyton Manning explodes for 326 yards and three touchdowns as the Colts beat the Jaguars, 25-20. The Colts actually trailed late in the game, but when Manning hit Reggie Wayne with a four-yard TD, Indy pulled out their eighth win of the year.
Player of the Game: Peyton Manning