The Sprint Cup rookie will drive for Turner Scott Motorsports, which also fielded her ride in the opener at Daytona International Speedway.
Patrick has only one start at Talladega, finishing 13th in last year's Nationwide race for JR Motorsports.
"I'm thrilled that I get another chance to drive the No. 34," Patrick siad in a release. "We had a great run going in Daytona, and I'm hoping we can pick up where we left off.''
Patrick is 26th in the Sprint Cup standings where she is battling Ricky Stenhouse Jr. for rookie of the year.
