Trout says he feels better than he did Saturday when he was a late scratch but is still "a little bit stiff."
Manager Mike Scioscia said before the game that Trout would be back in the lineup Tuesday when the Angels open a series at Houston.
Josh Donaldson hit a two-run single and Coco Crisp and Lowrie added RBI hits in a four-run third inning against Jered Weaver (6-4) to give the A's their first home sweep of at least three games against the Angels since June 29-July 1, 2004.
Trout is batting .294 with 11 home runs and 38 RBIs this season.
The Angels also will get slugger Josh Hamilton back this week as he will be activated and join the team on Tuesday in Houston for the first time since tearing a ligament in his left thumb sliding headfirst into first base April 8.
Los Angeles optioned right-hander Jarrett Grube to Triple-A Salt Lake after the game to make room for Hamilton.
The Associated Press contributed to this report.