The former American League MVP grounded out weakly in his only at-bat, and he failed to make a play on J.D. Martinez's long fly to left in the second, allowing it to bounce for a double.
Efren Navarro started for the second straight game, going 1-for-3 with a solo home run in the second and an RBI groundout in the sixth inning before J.B. Shuck replaced him in left to start the top of the ninth. On Friday, Navarro replaced Hamilton in left to begin the fourth inning and had two hits, including an RBI single in the sixth inning that drove in Kole Calhoun for the winning run.
Hamilton was batting .326 in the Angels' past 11 games, boosting his season average to .293. He has just five homers and 29 RBIs.
The Associated Press contributed to this report.