Skaggs held the Orioles hitless before walking off the mound with two outs in the fifth inning. He had retired 14 straight batters before issuing a walk to Steve Pearce. Then he motioned to the dugout immediately after throwing one pitch to Caleb Joseph.
After a quick consultation at the mound, Skaggs headed toward the dugout, briefly gripping his left arm on the way.
"It's always a concern whenever your arm's sore and can't feel your fingers," Skaggs said after the game. "I felt it was one of the better games I felt all year. It's frustrating."
Skaggs was replaced by Mike Morin in the game tied 0-0. Morin immediately gave up a single to Joseph.
Skaggs struck out seven and walked two.
Information from the Associated Press was used in this report.