Prather, who is averaging 17 points a game, missed the last two outings with a badly bruised right knee.
Coach Billy Donovan says Prather is running and practicing with contact. Donovan, though, is unsure how much he will get out of the 6-foot-6 senior: "How much he'll play is really, really hard to say. I'm doubtful he's play much. That's my guess."
The Gators (14-2, 3-0 SEC) have won eight in a row and 13 of 14, the only loss a buzzer-beater at then-No. 12 UConn early last month.