| MLB Single-Season (Post 1900) Pitching Leaders - Saves | |||||||||||||||
| PLAYER | YR | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 1 | Francisco Rodriguez | 2008 | 76 | 0 | 0 | 0 | 68.1 | 54 | 17 | 34 | 77 | 2 | 3 | 62 | 2.24 |
| 2 | Bobby Thigpen | 1990 | 77 | 0 | 0 | 0 | 88.2 | 60 | 18 | 32 | 70 | 4 | 6 | 57 | 1.83 |
| 3 | John Smoltz | 2002 | 75 | 0 | 0 | 0 | 80.1 | 59 | 29 | 24 | 85 | 3 | 2 | 55 | 3.25 |
| 4 | Eric Gagne | 2003 | 77 | 0 | 0 | 0 | 82.1 | 37 | 11 | 20 | 137 | 2 | 3 | 55 | 1.20 |
| 5 | Randy Myers | 1993 | 73 | 0 | 0 | 0 | 75.1 | 65 | 26 | 26 | 86 | 2 | 4 | 53 | 3.11 |
| 6 | Trevor Hoffman | 1998 | 66 | 0 | 0 | 0 | 73.0 | 41 | 12 | 21 | 86 | 4 | 2 | 53 | 1.48 |
| 7 | Mariano Rivera | 2004 | 74 | 0 | 0 | 0 | 78.2 | 65 | 17 | 20 | 66 | 4 | 2 | 53 | 1.94 |
| 8 | Eric Gagne | 2002 | 77 | 0 | 0 | 0 | 82.1 | 55 | 18 | 16 | 114 | 4 | 1 | 52 | 1.97 |
| 9 | Dennis Eckersley | 1992 | 69 | 0 | 0 | 0 | 80.0 | 62 | 17 | 11 | 93 | 7 | 1 | 51 | 1.91 |
| 10 | Rod Beck | 1998 | 81 | 0 | 0 | 0 | 80.1 | 86 | 27 | 20 | 81 | 3 | 4 | 51 | 3.02 |
| PLAYER | YR | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 11 | Mariano Rivera | 2001 | 71 | 0 | 0 | 0 | 80.2 | 61 | 21 | 12 | 83 | 4 | 6 | 50 | 2.34 |
| 12 | Francisco Cordero | 2004 | 67 | 0 | 0 | 0 | 71.2 | 60 | 17 | 32 | 79 | 3 | 4 | 49 | 2.13 |
| 13 | Jose Valverde | 2011 | 75 | 0 | 0 | 0 | 72.1 | 52 | 18 | 34 | 69 | 2 | 4 | 49 | 2.24 |
| 14 | Dennis Eckersley | 1990 | 63 | 0 | 0 | 0 | 73.1 | 41 | 5 | 4 | 73 | 4 | 2 | 48 | 0.61 |
| 15 | Jeff Shaw | 1998 | 73 | 0 | 0 | 0 | 85.0 | 75 | 20 | 19 | 55 | 3 | 8 | 48 | 2.12 |
| 16 | Rod Beck | 1993 | 76 | 0 | 0 | 0 | 79.1 | 57 | 19 | 13 | 86 | 3 | 1 | 48 | 2.16 |
| 17 | Brian Fuentes | 2009 | 65 | 0 | 0 | 0 | 55.0 | 53 | 24 | 24 | 46 | 1 | 5 | 48 | 3.93 |
| 18 | Brian Wilson | 2010 | 70 | 0 | 0 | 0 | 74.2 | 62 | 15 | 26 | 93 | 3 | 3 | 48 | 1.81 |
| 19 | Lee Smith | 1991 | 67 | 0 | 0 | 0 | 73.0 | 70 | 19 | 13 | 67 | 6 | 3 | 47 | 2.34 |
| 20 | Armando Benitez | 2004 | 64 | 0 | 0 | 0 | 69.2 | 36 | 10 | 21 | 62 | 2 | 2 | 47 | 1.29 |
| PLAYER | YR | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 21 | Jason Isringhausen | 2004 | 74 | 0 | 0 | 0 | 75.1 | 55 | 24 | 23 | 71 | 4 | 2 | 47 | 2.87 |
| 22 | Joe Nathan | 2009 | 70 | 0 | 0 | 0 | 68.2 | 42 | 16 | 22 | 89 | 2 | 2 | 47 | 2.10 |
| 23 | Francisco Rodriguez | 2006 | 69 | 0 | 0 | 0 | 73.0 | 52 | 14 | 28 | 98 | 2 | 3 | 47 | 1.73 |
| 24 | Jose Valverde | 2007 | 65 | 0 | 0 | 0 | 64.1 | 46 | 19 | 26 | 78 | 1 | 4 | 47 | 2.66 |
| 25 | Chad Cordero | 2005 | 74 | 0 | 0 | 0 | 74.1 | 55 | 15 | 17 | 61 | 2 | 4 | 47 | 1.82 |
| 26 | Heath Bell | 2010 | 67 | 0 | 0 | 0 | 70.0 | 56 | 15 | 28 | 86 | 6 | 1 | 47 | 1.93 |
| 27 | Lee Smith | 1993 | 63 | 0 | 0 | 0 | 58.0 | 53 | 25 | 14 | 60 | 2 | 4 | 46 | 3.88 |
| 28 | Dave Righetti | 1986 | 74 | 0 | 0 | 0 | 106.2 | 88 | 29 | 35 | 83 | 8 | 8 | 46 | 2.45 |
| 29 | Bryan Harvey | 1991 | 67 | 0 | 0 | 0 | 78.2 | 51 | 14 | 17 | 101 | 2 | 4 | 46 | 1.60 |
| 30 | Jose Mesa | 1995 | 62 | 0 | 0 | 0 | 64.0 | 49 | 8 | 17 | 58 | 3 | 0 | 46 | 1.13 |
| PLAYER | YR | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 31 | Tom Gordon | 1998 | 73 | 0 | 0 | 0 | 79.1 | 55 | 24 | 25 | 78 | 7 | 4 | 46 | 2.72 |
| 32 | Mike Williams | 2002 | 59 | 0 | 0 | 0 | 61.1 | 54 | 20 | 21 | 43 | 2 | 6 | 46 | 2.93 |
| 33 | Trevor Hoffman | 2006 | 65 | 0 | 0 | 0 | 63.0 | 48 | 15 | 13 | 50 | 0 | 2 | 46 | 2.14 |
| 34 | John Axford | 2011 | 74 | 0 | 0 | 0 | 73.2 | 59 | 16 | 25 | 86 | 2 | 2 | 46 | 1.95 |
| 35 | Craig Kimbrel | 2011 | 79 | 0 | 0 | 0 | 77.0 | 48 | 18 | 32 | 127 | 4 | 3 | 46 | 2.10 |
| 36 | Bruce Sutter | 1984 | 71 | 0 | 0 | 0 | 122.2 | 109 | 21 | 23 | 77 | 5 | 7 | 45 | 1.54 |
| 37 | Dennis Eckersley | 1988 | 60 | 0 | 0 | 0 | 72.2 | 52 | 19 | 11 | 70 | 4 | 2 | 45 | 2.35 |
| 38 | Dan Quisenberry | 1983 | 69 | 0 | 0 | 0 | 139.0 | 118 | 30 | 11 | 48 | 5 | 3 | 45 | 1.94 |
| 39 | Randy Myers | 1997 | 61 | 0 | 0 | 0 | 59.2 | 47 | 10 | 22 | 56 | 2 | 3 | 45 | 1.51 |
| 40 | Duane Ward | 1993 | 71 | 0 | 0 | 0 | 71.2 | 49 | 17 | 25 | 97 | 2 | 3 | 45 | 2.13 |
| PLAYER | YR | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 41 | Bryan Harvey | 1993 | 59 | 0 | 0 | 0 | 69.0 | 45 | 13 | 13 | 73 | 1 | 5 | 45 | 1.70 |
| 42 | Jeff Montgomery | 1993 | 69 | 0 | 0 | 0 | 87.1 | 65 | 22 | 23 | 66 | 7 | 5 | 45 | 2.27 |
| 43 | Jose Mesa | 2002 | 74 | 0 | 0 | 0 | 75.2 | 65 | 25 | 39 | 64 | 4 | 6 | 45 | 2.97 |
| 44 | John Smoltz | 2003 | 62 | 0 | 0 | 0 | 64.1 | 48 | 8 | 8 | 73 | 0 | 2 | 45 | 1.12 |
| 45 | Bob Wickman | 2005 | 64 | 0 | 0 | 0 | 62.0 | 57 | 17 | 21 | 41 | 0 | 4 | 45 | 2.47 |
| 46 | Robb Nen | 2001 | 79 | 0 | 0 | 0 | 77.2 | 58 | 26 | 22 | 93 | 4 | 5 | 45 | 3.01 |
| 47 | Eddie Guardado | 2002 | 68 | 0 | 0 | 0 | 67.2 | 53 | 22 | 18 | 70 | 1 | 3 | 45 | 2.93 |
| 48 | Mariano Rivera | 1999 | 66 | 0 | 0 | 0 | 69.0 | 43 | 14 | 18 | 52 | 4 | 3 | 45 | 1.83 |
| 49 | Joe Borowski | 2007 | 69 | 0 | 0 | 0 | 65.2 | 77 | 37 | 17 | 58 | 4 | 5 | 45 | 5.07 |
| 50 | Antonio Alfonseca | 2000 | 68 | 0 | 0 | 0 | 70.0 | 82 | 33 | 24 | 47 | 5 | 6 | 45 | 4.24 |