| MLB Career Pitching Leaders - Earned Run Average | |||||||||||||||
| PLAYER | YRS | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 1 | Al Spalding | 3 | 65 | 61 | 53 | 8 | 539.2 | 559 | 107 | 26 | 41 | 48 | 12 | 1 | 1.78 |
| 2 | Ed Walsh | 14 | 430 | 315 | 250 | 57 | 2964.1 | 2346 | 598 | 617 | 1736 | 195 | 126 | 34 | 1.82 |
| 3 | Jonathan Papelbon | 4 | 268 | 3 | 0 | 0 | 298.0 | 215 | 61 | 77 | 346 | 14 | 11 | 151 | 1.84 |
| 4 | Addie Joss | 9 | 286 | 260 | 234 | 45 | 2327.0 | 1888 | 488 | 364 | 920 | 160 | 97 | 5 | 1.89 |
| 5 | Jim Devlin | 2 | 129 | 129 | 127 | 9 | 1181.0 | 1183 | 248 | 78 | 263 | 65 | 60 | 0 | 1.89 |
| 6 | Jack Pfiester | 8 | 149 | 128 | 75 | 17 | 1067.1 | 869 | 240 | 293 | 503 | 71 | 44 | 0 | 2.02 |
| 7 | Joe Wood | 14 | 225 | 158 | 121 | 28 | 1436.1 | 1138 | 324 | 421 | 989 | 116 | 57 | 11 | 2.03 |
| 8 | Takashi Saito | 3 | 236 | 0 | 0 | 0 | 245.1 | 171 | 56 | 77 | 297 | 15 | 10 | 83 | 2.05 |
| 9 | Mordecai Brown | 14 | 481 | 332 | 271 | 55 | 3172.1 | 2708 | 725 | 673 | 1375 | 239 | 130 | 49 | 2.06 |
| 10 | Joakim Soria | 2 | 172 | 0 | 0 | 0 | 189.1 | 129 | 44 | 54 | 210 | 7 | 8 | 89 | 2.09 |
| PLAYER | YRS | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 11 | John Ward | 17 | 292 | 261 | 244 | 24 | 2461.2 | 2317 | 575 | 253 | 920 | 164 | 102 | 3 | 2.10 |
| 12 | Christy Mathewson | 17 | 635 | 551 | 434 | 79 | 4780.2 | 4218 | 1133 | 844 | 2502 | 373 | 188 | 28 | 2.13 |
| 13 | Rube Waddell | 13 | 407 | 340 | 261 | 50 | 2961.1 | 2460 | 711 | 803 | 2316 | 193 | 143 | 5 | 2.16 |
| 14 | Walter Johnson | 21 | 802 | 666 | 531 | 110 | 5914.2 | 4913 | 1424 | 1363 | 3509 | 417 | 279 | 34 | 2.17 |
| 15 | Glenn Liebhardt | 4 | 90 | 66 | 49 | 7 | 612.2 | 543 | 148 | 183 | 280 | 36 | 35 | 2 | 2.17 |
| 16 | Mellie Wolfgang | 5 | 77 | 27 | 15 | 3 | 326.0 | 268 | 79 | 95 | 111 | 15 | 14 | 0 | 2.18 |
| 17 | Erv Lange | 1 | 36 | 22 | 10 | 2 | 190.0 | 162 | 47 | 55 | 87 | 12 | 11 | 2 | 2.23 |
| 18 | Jake Weimer | 7 | 191 | 180 | 143 | 21 | 1472.2 | 1227 | 365 | 493 | 657 | 97 | 69 | 2 | 2.23 |
| 19 | Orval Overall | 7 | 218 | 182 | 133 | 30 | 1535.1 | 1232 | 381 | 551 | 935 | 108 | 71 | 12 | 2.23 |
| 20 | Jocko Flynn | 2 | 32 | 29 | 28 | 2 | 257.0 | 207 | 64 | 63 | 146 | 23 | 6 | 1 | 2.24 |
| PLAYER | YRS | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 21 | Tommy Bond | 8 | 322 | 314 | 294 | 35 | 2779.2 | 2857 | 695 | 178 | 860 | 193 | 115 | 0 | 2.25 |
| 22 | Mariano Rivera | 14 | 917 | 10 | 0 | 0 | 1090.0 | 848 | 273 | 256 | 1006 | 71 | 52 | 526 | 2.25 |
| 23 | Bill James | 4 | 84 | 61 | 44 | 5 | 541.2 | 469 | 137 | 199 | 253 | 37 | 21 | 2 | 2.28 |
| 24 | Will White | 10 | 403 | 401 | 394 | 36 | 3542.2 | 3440 | 896 | 496 | 1041 | 229 | 166 | 0 | 2.28 |
| 25 | Babe Ruth | 22 | 163 | 148 | 107 | 17 | 1221.1 | 974 | 309 | 441 | 488 | 94 | 46 | 4 | 2.28 |
| 26 | Ed Reulbach | 13 | 399 | 300 | 201 | 40 | 2632.1 | 2118 | 668 | 892 | 1138 | 182 | 106 | 13 | 2.28 |
| 27 | Frank Arellanes | 3 | 74 | 49 | 25 | 2 | 409.2 | 358 | 104 | 85 | 148 | 24 | 22 | 8 | 2.28 |
| 28 | Rube Kroh | 6 | 36 | 25 | 13 | 3 | 216.1 | 182 | 55 | 67 | 92 | 14 | 9 | 0 | 2.29 |
| 29 | Nick Maddox | 4 | 93 | 72 | 47 | 9 | 605.1 | 487 | 154 | 170 | 193 | 43 | 20 | 1 | 2.29 |
| 30 | Jim Scott | 9 | 317 | 226 | 123 | 26 | 1892.0 | 1624 | 483 | 609 | 945 | 107 | 113 | 9 | 2.30 |
| PLAYER | YRS | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 31 | Reb Russell | 9 | 242 | 148 | 81 | 24 | 1291.2 | 1128 | 335 | 267 | 495 | 81 | 59 | 13 | 2.33 |
| 32 | Andy Coakley | 9 | 150 | 124 | 87 | 11 | 1072.1 | 1021 | 280 | 314 | 428 | 58 | 59 | 3 | 2.35 |
| 33 | Eddie Plank | 17 | 623 | 529 | 410 | 69 | 4495.2 | 3958 | 1174 | 1072 | 2246 | 326 | 194 | 23 | 2.35 |
| 34 | Larry Corcoran | 8 | 277 | 268 | 256 | 22 | 2392.1 | 2147 | 626 | 496 | 1103 | 177 | 89 | 2 | 2.36 |
| 35 | Rube Foster | 5 | 138 | 103 | 60 | 15 | 842.1 | 726 | 221 | 305 | 294 | 58 | 34 | 3 | 2.36 |
| 36 | Bill Chappelle | 3 | 35 | 16 | 9 | 1 | 177.2 | 167 | 47 | 59 | 62 | 7 | 7 | 1 | 2.38 |
| 37 | George McQuillan | 10 | 273 | 173 | 105 | 17 | 1576.1 | 1382 | 417 | 401 | 590 | 85 | 89 | 14 | 2.38 |
| 38 | Eddie Cicotte | 14 | 502 | 361 | 249 | 35 | 3223.1 | 2897 | 853 | 827 | 1374 | 208 | 149 | 25 | 2.38 |
| 39 | Ed Killian | 8 | 213 | 180 | 149 | 22 | 1598.1 | 1463 | 423 | 482 | 516 | 102 | 78 | 6 | 2.38 |
| 40 | Billy Wagner | 14 | 782 | 0 | 0 | 0 | 833.2 | 563 | 221 | 278 | 1092 | 40 | 38 | 385 | 2.39 |
| PLAYER | YRS | G | GS | CG | SH | IP | H | ER | BB | SO | W | L | SV | ERA | |
| 41 | Doc White | 13 | 427 | 363 | 262 | 45 | 3041.0 | 2743 | 808 | 670 | 1384 | 189 | 156 | 5 | 2.39 |
| 42 | Harry Coveleski | 9 | 198 | 151 | 83 | 13 | 1248.0 | 1070 | 332 | 376 | 511 | 81 | 55 | 9 | 2.39 |
| 43 | Elmer Steele | 5 | 75 | 43 | 20 | 3 | 418.0 | 367 | 112 | 68 | 147 | 18 | 24 | 3 | 2.41 |
| 44 | Carl Lundgren | 8 | 179 | 149 | 125 | 19 | 1322.0 | 1129 | 355 | 476 | 535 | 91 | 55 | 6 | 2.42 |
| 45 | Nap Rucker | 10 | 336 | 272 | 186 | 38 | 2375.1 | 2089 | 639 | 701 | 1217 | 134 | 134 | 14 | 2.42 |
| 46 | Ed Summers | 5 | 138 | 112 | 79 | 9 | 999.0 | 930 | 269 | 221 | 362 | 68 | 45 | 3 | 2.42 |
| 47 | Jeff Tesreau | 7 | 247 | 206 | 123 | 27 | 1679.0 | 1350 | 453 | 572 | 880 | 115 | 72 | 9 | 2.43 |
| 48 | Joe Benz | 9 | 251 | 163 | 75 | 17 | 1359.2 | 1225 | 367 | 334 | 539 | 76 | 75 | 3 | 2.43 |
| 49 | Jim McCormick | 11 | 492 | 485 | 466 | 33 | 4275.2 | 4092 | 1155 | 749 | 1704 | 265 | 214 | 1 | 2.43 |
| 50 | Terry Larkin | 6 | 176 | 176 | 172 | 9 | 1567.1 | 1627 | 424 | 124 | 406 | 89 | 80 | 0 | 2.43 |
