Boone's wife, Pat, said he had been hospitalized for six months
following complications from surgery.
"It's a blessing," she said. "He had a great life."
Ray Boone played from 1948-60 with six teams over his major-league career, including the Indians, Tigers, White Sox, Athletics, Braves and Red Sox. He had a career .275 batting average,
with 151 home runs and 737 RBI.
Boone was a two-time All-Star for the Tigers in 1954 and 1956, but it is his family tree for which he likely will be most remembered.
"We were the first three-generation family," Pat Boone said.
"We're not the only one, but we were the first."
Boone was hitting .355 in the Texas League in late 1948 when he was called up to replace Lou Boudreau in the field when the Cleveland shortstop-manager was hurt.
A converted catcher, Boone was called up in time to earn a World Series share. By his third season, he was the Indians' regular shortstop.
Boone became a scout for the Red Sox after he played his final MLB season with the club, in 1960. The team held a moment of silence before Sunday night's Game 4 of the ALCS.
The Boone family had a reunion of sorts at the 2003 All-Star Game. They were the first baseball family to send three generations to the All-Star Game.
Bret and younger brother Aaron were both chosen for the Midsummer Classic. So the rest of the family came along for the show.
"Anybody that's not proud in this situation, there's something wrong with them," Ray said at the time.
A funeral for Boone has been scheduled for Sunday afternoon at the First United Methodist Church in suburban El Cajon, Calif., a San Diego suburb.
Information from ESPN's Peter Gammons and The Associated Press was used in this report.