A team trainer went out to watch Sabathia while he warmed up before the inning. He gave up a one-out double to Brett Carroll, then manager Joe Girardi and a trainer came out to check on the left-hander again before taking him out of the game.
The team said Sabathia is day to day and that no tests are planned.
Sabathia gave up one run and three hits in 1 1/3 innings. He entered 6-4 with a 3.67 ERA.
The 2007 AL Cy Young Award winner, Sabathia was the Yankees' biggest offseason pitching acquisition. He signed a $161 million, seven-year contract with New York after spending 2008 with Cleveland and Milwaukee.