Marlins 1
(0-1, 0-1 away)
Mets 7
(1-0, 1-0 home)
1:10 PM ET, April 5, 2010
Citi Field, New York, NY
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | |
| FLA | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 6 | 3 |
| NYM | 2 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | - | 7 | 9 | 1 |
W: J. Santana (1-0)
L: J. Johnson (0-1)
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NEW YORK - APRIL 05: Fans outside the stadium prior to the start of the game between the Florida Marlins of the New York Mets during their Opening Day game at Citi Field on April 5, 2010 in New York, New York. (Photo by Chris McGrath/Getty Images)