"I had a couple in the field that I didn't come through," said Andino, who was charged with one error in the game. "The pitchers kept us in it we didn't come through when we needed to."
Twice after Wieters hit his sixth home run of the season, Andino ended up the final out of an inning leaving a potential go-ahead run on base.
"You got some situations where we you get that man on third base and one out, that was a kick in the pants," Orioles manager Buck Showalter said. "Just so many good things happened to get back in that game. We just couldn't get over the hump."
Uehara (1-1) set the Blue Jays down in order in the 10th, striking out Corey Patterson and Jose Bautista to end the inning. Shawn Camp (1-1) responded by shutting down Baltimore in the top half of the 11th, before Lind connected off Uehara in the bottom half.
"It was just a splitter that was up in the zone," said Wieters, the Orioles catcher. "That's something where if it has his normal action, it's probably a ground ball. But he made a mistake and give Lind credit, he hit it."
It also cost Blue Jays starter Carlos Villanueva the chance to win for the fourth time in five starts since entering Toronto's rotation May 23. The 27-year-old, used exclusively as a reliever last season, gave up three runs over six strong innings.
Jason Frasor replaced him with two on and none out in the seventh, and drew jeers from the announced crowd of 15,592 with a wild pitch that advanced the runners. Andino's sacrifice fly scored Luke Scott to make it 4-2. Mark Reynolds then came home on J.J. Hardy's third hit of the game, a double that trimmed Toronto's lead to 4-3.
Aaron Hill's second homer of the year made it 5-3 in the seventh. The deep shot came one out after Wieters threw out J.P. Arencibia trying to reach third base on a pitch in the dirt that momentarily bounced away from the Orioles catcher.
Chris Jakubauskas started for Baltimore and gave up four runs in 5 1/3 innings.
"I didn't have my best stuff tonight," Jakubauskas said. "It was kind of one of those nights. I was kind of all over the place I was falling behind pitching 1-0, 2-0 to a lot of guys."
Toronto built its early lead on Lind's RBI double in the first and a Bautista fielder's choice in the third. The Blue Jays scored two more in the fourth when Hill reached on a bunt single, Jayson Nix was hit by a pitch and Yunel Escobar had an RBI single. Nix later scored on a ground out.
Toronto left the bases loaded in the bottom of the eighth when Arencibia grounded into a fielder's choice force out at home with one out and Edwin Encarnacion flied out to right. The result prevented the Orioles from moving past the Blue Jays and out of last in the AL East.
It also gave Baltimore 15 straight losses at the Rogers Centre.
"We've had our struggles for a while, period," said Showalter. "So we don't look at some place. Our guys, other than going through customs, enjoy playing here."
Showalter said 2B Brian Roberts began "stressful exertion activities" at the team's spring training complex. ... Orioles Hall of Famer Brooks Robinson was released from a Baltimore hospital Monday after follow-up treatment for an infection and fever. "That's beautiful," Showalter said. "That's the best news I've heard all day." Baltimore 1B Derrek Lee came off the bereavement list Tuesday after missing a weekend series against Tampa Bay to attend his grandfather's funeral. ... Zach Stewart will pitch Thursday for Toronto, with Jo-Jo Reyes and Brandon Morrow each getting an extra day of rest. ... Blue Jays GM Alex Anthopoulos said OF Travis Snider's swing changes at Triple-A Las Vegas are helping restore his power. "He looks a lot better at the plate," Anthopoulos said. ... The Blue Jays' Jesse Litsch is scheduled to pitch for Class-A Lansing (Mich.) on June 18. ... Baltimore entered Tuesday night on a 14-game losing streak at the Rogers Centre. Its last win in Toronto came on Aug. 7, 2009. ... Frasor made his 440th appearance for the Jays, moving past Dave Stieb into third on the all-time list.