CHICAGO -- A native Chicagoan who was a Cubs fan, Adam Rosales took a little extra satisfaction Thursday night when he homered in the 10th inning.
"It feels really special," Rosales said. "I had family in the stands and a lot of friends. I grew up a Cubs fan, I grew up coming here when it was Comiskey (Park). Just to play on this field is a great opportunity, and to do that is just unbelievable to me."
Rosales' fourth homer of the season came off White Sox reliever Matt Thornton (0-2), one of a season-high four homers for the A's.
The A's have won six of seven and 17 of 20. Oakland is 12-2 during a 17-day stretch without a day off.
"The guys have just been awesome, they've been playing really well, a great team chemistry, guys coming up big and getting big hits and pitchers keeping us in the ballgame," Rosales said. "It's been a great start to the season."
Oakland right fielder Reddick had two of the biggest plays of the night.
"Nobody's really challenged my arm this year," Reddick said. "That's one thing I take pride in, that's the best part of my game on defense, throwing guys out. For them to actually try that made me feel really good that there are some guys that are going to try and run on that."
And Reddick's homer in the seventh tied it 4-all.
"It's hard to pick one," Reddick said when asked which play was more crucial. "They're both equally as important. The throw-out saves a run and if that run scores, we lose in the ninth.
"And, obviously, if you don't hit the home run, we don't go into extra innings and win the ballgame," Reddick added. "It's harder to pick one. You've got to look at them both the same way and look at them as saving the ballgame."
The White Sox have lost nine of their last 10 games and have been outscored 47-26 in their last nine games. Chicago has lost all four games against Oakland this season.
"We need to start winning some games or we might be saying bye to some people in July," White Sox second baseman Gordon Beckham said. "Hopefully, we can start winning and get a streak going."
White Sox starter Jose Quintana went 7 2/3 innings, giving up four runs on seven hits. He did not walk a batter but gave up three home runs.
Oakland starter Dan Straily pitched seven innings, gave up four runs on six hits, walked two and struck out three.
"I thought (Straily) pitched really well and I think his confidence has gotten to a point where he can give up some runs and still stay with it," A's manager Bob Melvin said. "Whereas earlier in the season it might have snowballed or cratered on him a little bit. It was impressive."
After Straily retired the first seven batters he faced, the White Sox scored three runs in the bottom of the third.
Beckham singled to center, but was forced at second when Flowers hit into a fielder's choice. De Aza doubled down the right field line, scoring Flowers.
The A's broke up Quintana's perfect game with two outs in the fourth when Cespedes drove a 1-1 pitch into the left-center stands to make it 3-1.
Oakland closed the gap to 3-2 in the top of the fifth when Nate Freiman led off with a single to center and scored on Rosales' double just inside the third base line.
Beckham led off the fifth with a walk, Flowers' double pushed Beckett to third and De Aza singled to score Beckham.
Oakland again closed Chicago's lead to one run in the sixth when Cespedes hit his second homer of the game -- and 13th this year -- a one-out drive to right-center.
The A's tied it at 4 in the seventh on Reddick's longball to right field, his second of the season.
The White Sox played without manager Robin Ventura, who was excused from Thursday and Friday's games to attend his daughter's graduation in California. Bench coach Mark Parent filled in for Ventura on Thursday, while pitching coach Don Cooper will manage Friday.
Prior to the game, the White Sox placed right-handed pitcher Jake Peavy on the 15-day disabled list (retroactive to June 5) with a broken rib. ... The 12 combined extra-inning runs scored by the White Sox and Mariners in Wednesday's 16-inning marathon tied the American league record for the fourth time, the most recently occurring in 1983. ... Brandon Moss's three-run homer in the seventh inning of Wednesday's game at Milwaukee was the 12,000th homer in A's team history. . Former NBA star and Fox Sports TV personality John Salley threw out the first pitch. ... Attendance was 21,156. ... Friday's starters will be Oakland's Jarrod Parker (4-6, 4.90) vs. Chicago's Chris Sale (5-3, 2.44). The White Sox are scheduled to start four left-handers in a series for the first time since July 21-24, 1980, against the Royals in Kansas City.