Reyes was diagnosed in early March with a hyperactive thyroid, and doctors prescribed rest and a change in diet. He was told not refrain from physical activity and was monitored and tested weekly in New York.
Mets general manager Omar Minaya said Reyes will resume full workouts Wednesday.
"It's a good sign for us today and, hopefully, it will be a good sign for the rest of the year," Minaya said. "Today is a good day."
Reyes was limited to 36 games last season because of a hamstring injury. He was pulled from stretching prior to what would have been his spring training debut March 5 when team doctors decided the abnormal results from his physical warranted further testing.
His only game action since May was an intrasquad scrimmage just before the start of exhibition play.
Though manager Jerry Manuel originally said Reyes likely needed 10 spring training games to be ready for regular-season play, Minaya did not want to speculate whether Reyes could appear in the April 5 opener against the Florida Marlins.
"Let's see how things go," Minaya said. "We are not going to say he is not going to be ready, but let's see when he comes out here how he gets himself prepared. The good thing is he came to camp in excellent shape. He is excited about being here, we are excited about him being here, but as far as Opening Day goes, we don't know."