Jason Heyward, who has hit leadoff in all but two games this season, hit fifth.
Manager Fredi Gonzalez said he may give La Stella, who is hitting .364, a long look in the leadoff spot.
The change was made as the Braves have lost two straight and five of seven to fall out of first place in the NL East. The Braves, who have struggled offensively most of the season, scored a combined three runs in their past two losses.
Gonzalez said he wants La Stella, the second baseman who was called up from the minors on May 28, "to do his thing."
"He doesn't have to change his approach," Gonzalez said.
Gonzalez said he had circled Wednesday's noon start as a good opportunity to give starters a rest in the middle of a long stretch of games.
"It usually turns out pretty good," Gonzalez said.
Heyward is hitting .254 with eight homers, 27 RBIs and nine stolen bases. Heyward provides speed at the top of the lineup and has lifted his batting average following a slow start in April. He also provides another power bat with Evan Gattis and Freddie Freeman in the middle of the lineup.
"I think the world of Jason Heyward," Gonzalez said. "I think he can hit anywhere in the lineup and be productive. That's why he's hitting fifth."
Information from the Associated Press was used in this report.