Izturis has played 11 seasons, including the past three in Baltimore. He played only 18 games for the Orioles last season, spending much of the year on the disabled list with nerve irritation in his right elbow. He also missed time with a strained groin.
Perez has 32 career appearances and was 1-0 with a 3.60 ERA for Philadelphia last season.
The Brewers also invited catcher Anderson De La Rosa, left-hander Jed Bradley and right-hander Taylor Jungmann to spring training.