Officials confirmed the 115-pound main event to ESPN.com on Thursday. The card will be held inside The Chelsea at The Cosmopolitan and air on UFC Fight Pass, its Internet subscription service.
Fight Night is the first of three scheduled UFC events in three days, all in Las Vegas. The Ultimate Fighter 22 Finale is scheduled for Dec. 11 and will be headlined by a featherweight matchup between Frankie Edgar and Chad Mendes. On Dec. 12, UFC 194, featuring a featherweight title unification bout between Jose Aldo and Conor McGregor, will take place at the MGM Grand Garden Arena.
One of the fastest rising athletes on the roster, VanZant (6-1), 21, signed a multifight contract extension with UFC on Friday. Fighting out of Team Alpha Male in Sacramento, California, she is 3-0 within the promotion, including a submission win against Alex Chambers at UFC 191 earlier this month.
ESPN.com ranks VanZant as the No. 9 strawweight in the world.
Calderwood (10-1) is a former contestant on The Ultimate Fighter reality series. A native of Scotland, she holds a 2-1 record inside the Octagon, including a hard-fought decision win over Cortney Casey at a July event in Glasgow, Scotland.
In addition to the main event, UFC officials confirmed a lightweight contest between Jim Miller (25-6) and Michael Chiesa (12-2) and a welterweight bout between John Howard (23-11) and Tim Means (24-7-1).