Sources confirmed to ESPN.com the bout will headline the UFC event, following an initial report by Brazilian news source, Tatame. UFC president Dana White confirmed the matchup earlier this week, but did not reveal a date.
The contest should go a long way in clearing up the 185-pound title picture. Belfort (22-10) shook up the division last month, knocking out top contender Michael Bisping in the second round.
The Brazilian is 3-0 at 185 pounds since a first-round KO loss to champion Anderson Silva in February 2011. He suffered a submission loss to light heavyweight champion Jon Jones at 205 pounds in September.
Rockhold (10-1) will carry a nine-fight win streak into his UFC debut. The California native captured the Strikeforce title with a unanimous decision win over Ronaldo Souza in September 2011 and went on to successfully defend it twice.
Originally scheduled for a third defense against Lorenz Larkin, Rockhold suffered a wrist injury that's kept him out of action since July. He never has fought outside the U.S. Belfort, meanwhile, has fought internationally in his previous three fights.