Team officials say the Sixers' leading scorer has a fracture and tear in his right shoulder but will not need surgery. Brand was hurt Wednesday night in a 93-88 win against Milwaukee.
"It's unfortunate that this happened, but we're starting rehab right away and I'm going to do everything I can to get back as soon as possible," Brand said in a statement released by the team Thursday.
"While I'm disappointed that I can't be on the court, during this time I'm going to continue to support my teammates and the coaches in any way they need me."
Brand is averaging 15.9 points and 9.8 rebounds per game this season.
A playoff team last season, the 76ers struggled to a 9-14 start before firing coach Maurice Cheeks last week. They
are 2-0 under interim coach Tony DiLeo.
Brand signed a five-year, $80 million contract on July 9 after two seasons with the Chicago Bulls, followed by seven seasons with the Los Angeles Clippers. He was limited to only eight games last season with the Clippers because of a left Achilles tendon injury.
Information from The Associated Press was used in this report.