Vazquez, of MTV fame, announced the news Wednesday on The Wendy Williams Show. The couple has been engaged for five years and have a son, Kiyan, who will turn 3 in March.
Vazquez said on the show there will be plenty of people invited since "everybody has been waiting for it for so long, we might as well invite everybody to come hang out."
Anthony also confirmed the impending nuptials after scoring 27 points in Denver's 115-97 over the Orlando Magic on Wednesday night.
"We're very happy," Anthony said. He added jokingly, "We've been working on this for years. I've probably got the longest engagement ever."
Anthony did say he hopes the wedding takes place late in the summer. After all, the Nuggets have their sights set on reaching the NBA Finals in June.
"We're looking forward to the summer but hopefully, not at the beginning of the summer," Anthony said.