CLEVELAND -- Mike Brown watched the blood drip off Chris Bosh's face earlier this week and decided that wasn't going to happen to his guys.
With nothing left to play for, Brown doesn't want to risk injury to LeBron James or another one of his starters. Cleveland's coach benched most of them Friday, allowing Indiana to escape with a 116-113 victory for the Pacers' ninth win in 11 games.
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James and Williams were both healthy scratches, while Jamison bruised his foot in a loss at Chicago on Thursday.
"I'm human just like everybody else," Brown said. "When you see Bosh get hit and Antawn's ankle and stuff like that, you do get a little worried."
Bosh needed surgery this week to repair a nasal fracture after getting hurt in Cleveland and will miss the first round of the playoffs, should Toronto earn the eighth seed.
With home-court advantage clinched through the NBA finals, Brown hasn't ruled out benching James for the rest of the regular season. Cleveland hosts Orlando on Sunday in what could be a prelude to an Eastern Conference finals rematch, then closes the regular season at Atlanta on Wednesday.
"There's a chance," Brown said. "I talked about that with my staff and I talked about it a little bit with [James], too. We'll take that one game at a time and see how it goes."
The Pacers were happy to take advantage of the Cavaliers' cautious ways, ending a 10-game losing streak in Cleveland.
Granger's 3-pointer with 1:22 left gave the Pacers a 108-106 lead. They never trailed again, but didn't secure the victory until Anthony Parker's turnaround 3-pointer at the buzzer fell well short of the rim.
"It's a great confidence win," Granger said. "I don't care who isn't playing for them. They're still a very good team."
Parker's 3-pointer with 3.9 seconds left rattled around before falling, pulling Cleveland within one in the final seconds. Granger was fouled and made both free throws, leaving the Cavaliers one final shot.
Zydrunas Ilgauskas took the inbounds pass and flipped it to Parker, who struggled to get off an awkward shot from well beyond the 3-point line as the buzzer sounded.
J.J. Hickson tied his career high with 21 points and added 10 rebounds, while Sebastian Telfair set a season high with 21 in just his second game with the Cavaliers.
Telfair joined the Cavaliers as part of the three-team trade that also brought Jamison at the trade deadline. Telfair couldn't break into Cleveland's rotation until Brown sat his regulars Thursday, but he hasn't shown any rust.
Telfair has scored 29 points and made 12-of-21 shots in two games.
"It's a good team and they've had a lot of success before I got here," Telfair said. "It takes getting on the court to really feel part of the team."
With so many regulars missing, the Cavaliers relied heavily on reserves. Jamario Moon started for the first time this season and finished with a season-high 15 points, while Ilgauskas had 14 off the bench. Parker remained a starter and scored 17 points.
Cleveland was whistled for three technicals. Delonte West received a pair, both within two minutes from official Marc Davis, and was ejected with 6:48 left in the third quarter. West set a career high with 12 assists before getting tossed. Ilgauskas also got a technical in the first half for arguing a foul call with official Kane Fitzgerald.
Granger was 14 of 14 from the free-throw line. ... Granger entered averaging 24.2 points, but has now scored at least 30 in seven of his last 10 games. ... Indiana made 14 of 32 3-pointers. ... Cleveland fell to 1/3 this season without James. ... The loss ended Cleveland's third 11-game home winning streak of the season.