With Thompson not hitting, the Warriors got blown out in just their second loss of the season.
J.J. Barea scored 23 points in another big game filling in for injured point guard Deron Williams, and the Dallas Mavericks rolled to a 114-91 victory over a Golden State team missing the NBA's leading scorer and reigning MVP.
"That's 30 points and a lot of playmaking, so we've just got to collectively try and chip in," said Thompson, who had 10 points. "We had great looks. It was just one of those nights."
Thompson and Draymond Green each shot 4-of-15 from the field, with Green scoring 11.
Curry has a bruised lower left leg and might sit again Thursday at Houston. But the Warriors (29-2) still have the best 31-game start in NBA history, a game better than four teams, after their record 24-0 start.
"They were a little short-handed tonight. Might have made a little difference," Dallas guard Devin Harris said. "The attention that he brings in shotmaking and the way the offense flows with him out there, obviously was a little bit different tonight."
The Warriors looked out of sorts almost from the beginning with Curry watching from the bench in jeans and a black sport coat.
And Brandon Rush didn't play much defense against Nowitzki. First, he let Nowitzki go by him for a rare two-handed dunk, and soon after, he left Nowitzki alone at the 3-point line for a 75-49 Dallas lead midway through the third quarter.
The 23-point margin was Golden State's worst defeat since a 31-point loss to Houston in 2013, according to STATS. The worst loss during the title run last season was 15.
The Mavericks went up by 30 at 83-53 on a 3-pointer by Wesley Matthews, who had 13 points. The Warriors, who fell behind for good with 8 minutes left in the first quarter, didn't get closer than 17 after that.
Thompson didn't play in the fourth quarter, and interim coach Luke Walton went with reserves for the last 5 minutes in Golden State's third straight loss without Curry. The first two were last season.
Overall, the Warriors are 1-6 without Curry over the past three seasons and have been outscored by 101 points in 460 minutes with Curry off the floor this season. They are have outscored opponents by 482 points in 1,043 minutes with Curry on the floor.
"He's one of those rare players in this league that affects the entire game just by being on the court," Walton said. "Obviously, without him the spacing won't be as good."
Barea, who has been starting while Williams sits with a left hamstring strain, had at least 23 points for the third time in four games. He is 17-of-22 from 3-point range in those games after going 5-of-7 against the Warriors.
"J.J.'s been great, shooting the ball incredibly well but taking good shots," Harris said.
CURRY'S NOT THE ONLY ONE
"I think people forget we've got like four guys out," said Andre Iguodala, who had 12 points. "We've been playing at such a high level, that gets overlooked sometimes."
COUNT IT, OR DON'T
The Warriors matched a season high by allowing 14 3-pointers on 52 percent shooting. It was almost 15. Harris, who scored 13, banked in a half-court shot at the third-quarter buzzer, but the ruling that it was after the horn was quickly confirmed by a replay review.
Warriors: Coach Steve Kerr, out all season after complications from back surgery, made the trip to see how his back would hold up. He made a trip to Los Angeles in November. Walton said there was still no timetable for Kerr's return, although it could be as soon as this weekend.
Mavericks: Pachulia had his 17th double-double -- two more than all of last season in Milwaukee -- when he grabbed his 10th rebound with 2:30 remaining in the first half. He already had his 12 first-half points by then.
Warriors: At Houston on Thursday.
Mavericks: At Miami on Friday.
The Associated Press contributed to this report.
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Bismack Biyombo drains a jumper early in the first quarter against the Cavs.
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