Knicks coach Derek Fisher said that Anthony will have no minutes restriction against the 76ers.
"We hope there's been enough days where he can get back out there and not really have any limitations probably other than just a little bit of game condition," Fisher said. "So we'll have to kind of see how it goes early."
Anthony suffered the injury Tuesday against the Celtics when he rolled his ankle on the foot of referee Steve Anderson while running back on defense. X-rays on the ankle were negative, according to the team.
New York (20-22) lost both games without Anthony and is 0-4 in games in which Anthony is sidelined due to injury.
Anthony, 31, entered play Monday averaging 21.6 points, 7.6 rebounds and 3.8 assists per game.