The Pacers originally listed George's return as questionable, but the three-time All-Star did not return to action.
Pacers coach Frank Vogel said after the game that George was day-to-day and called the injury a lower leg contusion.
"He's moving around," Vogel said. "He'll be OK."
The bruised right leg is the same one George gruesomely broke in August 2014 when he ran into a basketball stanchion during a U.S. national team scrimmage in Las Vegas. He had surgery to repair the leg within hours of the injury and missed 74 games.
George left the court with under 5 minutes to play in the third quarter. He said after the game that he "just got kneed" and hoped it was "nothing serious."
George had 15 points and four rebounds at the time when he left. He was replaced by C.J. Miles, who stepped in and scored eight points in final 7½ minutes of the third quarter and finished with 19 points.