Davis played 4 minutes, 20 seconds and scored the Magic's first basket before being taken out of the game. It was not clear how he was injured.
"You never want to see a teammate injured," Orlando guard J.J. Redick said after the Magic lost their seventh straight, 113-97. "We have played without him before and we just have to continue to roll with the punches, and guys are going to have to step up."
Davis came into the game averaging 15.5 points and 7.5 rebounds in 40 games.
Kidd, who sat out the second half of Sunday's win over Atlanta, was again out with a sore lower back.
Afflalo, averaging 16.7 points, missed his second straight game with a strained left calf.