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Breaking down the Midwest Region

Updated: March 18, 2013, 3:59 PM ET
By Dana O'Neil | ESPN.com

Louisville was tabbed the overall No. 1 seed, which to the NCAA tournament selection committee apparently meant the Cardinals could handle the toughest region.

Because make no mistake, this is it.

Ten first impressions

1. Can you say brutal? Between them, the coaches of the Nos. 1, 2 and 3 seeds have 22 Final Four berths and six national championships. One (Mike Krzyzewski) already is in the Hall of Fame; another (Rick Pitino) could become one of the ...

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